Cannabinoids, Terpenes & Effects
High
A high is the set of mental and physical effects felt after consuming cannabis, usually caused by THC.
What a high means in cannabis use
In cannabis use, a high refers to the psychoactive experience produced primarily by THC (tetrahydrocannabinol), the main intoxicating compound in the plant. This experience can include changes in mood, perception, sensory awareness, time perception, and body sensation. The intensity and character of a high vary widely based on dose, product type, and individual sensitivity.
Historical understanding of the cannabis high
Historically, the cannabis high has been described in cultural, medicinal, and recreational contexts for thousands of years. Long before THC was identified in 1964, people recognized cannabis for its ability to alter consciousness and enhance relaxation or creativity. Modern cannabis science has since clarified that the high is caused by THC interacting with the endocannabinoid system, particularly CB1 receptors in the brain.
How THC creates a high in the brain
The high occurs when THC crosses the blood–brain barrier (a protective filter that controls what enters the brain) and alters normal neurotransmitter signaling. This can produce euphoria, relaxation, heightened sensory perception, increased appetite, and altered thinking. At higher doses, the high may include anxiety, dizziness, or impaired coordination, especially in inexperienced users.
How consumption method affects the high
The onset, duration, and intensity of a high depend heavily on how cannabis is consumed. Smoking or vaping produces a fast-onset, shorter-lasting high that peaks quickly. Edibles and beverages create a delayed but often stronger and longer-lasting high because THC is converted by the liver into 11-hydroxy-THC, a more potent metabolite. Terpenes also shape how a high feels, influencing whether it feels energizing, calming, or heavy.
Using the high to guide cultivation and products
In cultivation and product development, understanding the high guides strain breeding, harvest timing, and formulation. Growers may select cultivars for uplifting, relaxing, or balanced highs by adjusting cannabinoid and terpene profiles. Clear labeling helps consumers choose products aligned with their desired experience.
Common challenges and responsible use
Common challenges include overconsumption, unpredictable intensity, and tolerance buildup. Responsible dosing, patience with onset time, and awareness of duration help ensure a positive and controlled high.
Related terms:
THC, Psychoactive, Dosing, Onset Time, and Duration.
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